- as Richard Castle
- as Greg McClintock
- as Det. Kate Beckett
- as Dr. Lissa Akerman
- as Det. Javier Esposito
- as Dr. Valerie Monroe
- as Det. Kevin Ryan
- as Gina Cowell
- as Dr. Lanie Parish
- as Cesar Calderon
- as Captain Roy Montgomery
- as Manuel Calderon
- as Alexis Castle
- as Leonard Maloney
- as Martha Rodgers
- as Amy Porter
- as Mr. Dreyfus
- as Dr. Imani Phelps
- as Jerry Camden
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