- as Sheldon Cooper
- as Connie 'Meemaw' Tucker
- as Mary Cooper
- as Sheldon Cooper (Voice)
- as George Cooper, Sr.
- as Dr. John Sturgis
- as George Cooper Jr.
- as Veronica
- as Missy Cooper
- as Ms. MacElroy
- as Pastor Jeff
- as Mr. Givens
- as Principal Petersen
- as Peg (Voice)
- as Mayor Harrison
- as Tam
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Watch "Young Sheldon > A Political Campaign and a Candy Land Cheater":