- as Josephine Lightbourne
- as Dr. Abigail Griffin
- as Bellamy Blake
- as Octavia Blake
- as Raven Reyes
- as John Murphy
- as Echo
- as Jordan Green
- as Marcus Kane
- as Nathan Miller
- as Emori
- as Dr. Eric Jackson
- as Charmaine Diyoza
- as Niylah
- as Madi Griffin
- as Russell Lightbourne VII
- as Dr. Simone Lightbourne VI
- as Xavier / Dr. Gabriel Santiago
- as Jade Royal Guard
- as Priya Desai VII
- as Ryker Desai IX
- as Josephine Lightbourne
- as Gavin / Marcus Kane II
- as Miranda
- as Sheidheda
- as Cassius
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