- as Richard Castle
- as Himself
- as Kate Beckett
- as Mark Heller
- as M.E. Sidney Perlmutter
- as Alexis Castle
- as Javier Esposito
- as Nurse Lockhart
- as Lanie Parish
- as Mitch Greenberg
- as Kevin Ryan
- as Freddie Baker
- as Captain Victoria Gates
- as Leopold Malloy
- as Val Butler
- as Amanda Lowery
- as Nigel Malloy
- as Tommy
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