- as Sheldon Cooper
- as Mandy McAllister
- as Mary Cooper
- as Brenda Sparks
- as George Cooper, Sr.
- as Pastor Rob
- as George Cooper Jr.
- as Jim McAllister
- as Missy Cooper
- as Audrey McAllister
- as Connie 'Meemaw' Tucker
- as Bruce
- as Sheldon Cooper (Voice)
- as Rhonda
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