- as Jane Rizzoli
- as Special Agent Gabriel Dean
- as Dr. Maura Isles
- as Detective Darren Crowe
- as Barry Frost
- as Charles Hoyt
- as Vince Korsak
- as Senator Sam Conway
- as Frank Rizzoli, Sr.
- as Marisa Rodriguez
- as Angela Rizzoli
- as John Stark
- as Prison Guard #1
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