• 
  Anna Paquin
  as Sookie Stackhouse
• 
  Stephen Moyer
  as William Thomas „Bill“ Compton
• 
  Sam Trammell
  as Sam Merlotte
• 
  Ryan Kwanten
  as Jason Stackhouse
• 
  Rutina Wesley
  as Tara Mae Thornton
• 
  Nelsan Ellis
  as Lafayette Reynolds
• 
  Chris Bauer
  as Andrew „Andy“ Bellefleur
• 
  Carrie Preston
  as Arlene Bellefleur
• 
  Alexander Skarsgård
  as Eric Northman
• 
  Deborah Ann Woll
  as Jessica Hamby
• 
  Kristin Bauer van Straten
  as Pamela „Pam“ Swynford De Beaufort
• 
  Lauren Bowles
  as Holly Clearly
• 
  Joe Manganiello
  as Alcide Herveaux
• 
  Kelly Overton
  as Rikki Naylor
• 
  Robert Patrick
  as Jackson Herveaux
• 
  Rutger Hauer
  as Niall Brigant
• 
  Jurnee Smollett
  as Nicole Wright
• 
  Todd Lowe
  as Terry Bellefleur
• 
  Michael McMillian
  as Steve Newlin
• 
  Anna Camp
  as Sarah Newlin
• 
  Lucy Griffiths
  as Nora Gainesborough
• 
  Robert Kazinsky
  as Warlow
• 
  Arliss Howard
  as Truman Burrell