- as Lieutenant Matthew „Matt“ Casey
- as Scott Rice
- as Lieutenant Kelly Severide
- as Donna Robbins
- as April Sexton
- as Peter Mills
- as Capp
- as Gabriela „Gabby“ Dawson
- as Chief Wallace Boden
- as Cindy Herrmann
- as Lieutenant Christopher Herrmann
- as Elise Mills
- as Brian „Otis“ Zvonecek
- as Kim Burgess
- as Randy „Mouch“ McHolland
- as Sean Roman
- as Joe Cruz
- as Chaplain Orlovsky
- as Sylvie Brett
- as Tony
- as Dispatcher (Voice)
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