- as Dr. Shaun Murphy
- as Dr. Morgan Reznick
- as Dr. Neil Melendez
- as Dr. Alex Park
- as Dr. Claire Browne
- as Dr. Audrey Lim
- as Dr. Carly Lever
- as Dr. Aaron Glassman
- as Caroline Reznik
- as Ariel Reznik
- as Oliver Thomas
- as Bella Thomas
- as Nurse
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