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as Sheldon Cooper
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as A.V.
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as Mary Cooper
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as Pus
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as George Cooper, Sr.
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as Dr. Linkletter
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as George Cooper Jr.
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as President Hagemeyer
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as Missy Cooper
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as Brenda Sparks
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as Connie 'Meemaw' Tucker
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as Principal Petersen
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as Sheldon Cooper (Voice)
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as Roy
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as Coach Wayne Wilkins
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as Wade
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Watch "Young Sheldon > A Clogged Pore, a Little Spanish and the Future":